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Interestingly, autoreactive immature B cells that target CNS-specific antigens, such as myelin oligodendrocyte glycoprotein (MOG), undergo negative selection within the meninges, preventing their accumulation and potential autoimmune consequences [122]

doi: 10.1038/s41586-020-2338-1 2

Regulatory Status Snapshot Not approved as a therapeutic drug by major regulators Safety profile not established in large human populations Need help interpreting this evidence for your situation

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